|
KMID : 0603820170230040355
|
|
Journal of Experimental & Biomedical Science
2017 Volume.23 No. 4 p.355 ~ p.361
|
|
|
Antioxidants and Anti-inflammatory Effects of Fermented Houttuynia cordata Thunb and Scoria Mixture Extract
|
|
Lee Sung-Gyu
Kang Sang-Moon
Lee Kee-Young
Park Kwang-Lyul
Kang Hyun
|
|
|
Abstract
|
|
|
|
In this study, antioxidant and anti-inflammatory of fermented Houttuynia cordata Thunb and scoria mixture extract were investigated in vitro. Radical-scavenging activities of the ethanol extracts were examined by using α,α-diphenyl-β-picrylhydrazyl (DPPH) and 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS)) radicals assay. Consequently, we confirmed that fermented Houttuynia cordata Thunb and scoria mixture extract dependent removed DPPH and ABTS radical. Also, to confirm anti-inflammatory activity of ethanol extract, we treated fermented Houttuynia cordata Thunb and scoria mixture extract on BV-2 cell with LPS. The result showed that fermented Houttuynia cordata Thunb and scoria mixture extract concentration-dependent inhibited NO production. Therefore, fermented Houttuynia cordata Thunb and scoria mixture extract showed inhibition radical oxygen activities and inflammatory and have available for a pharmacological composition on neuritis-protection and treatment.
|
|
|
KEYWORD
|
|
|
Antioxidant, Anti-inflammatory, Scoria, Fermentation, Houttuynia cordata
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|